• acetyl hexapeptide-8, Argireline

    Acetyl Hexapeptide-8

    Acetyl hexapeptide-3, now acetyl hexapeptide-8, is also marketed under the name of Argireline™(Lipotec).  This peptide has the sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2 .  It is a cosmetic peptide that inhibits the SNARE complex formation and release. In laymans terms helps to relax muscels by limiting production and release of neuro transmitters that initiate and control the facial muscle intensity, resulting in the reduction of the degree of existing facial wrinkles. It has a demonstrated effectiveness against wrinkle development with regular use.

    In clinical studies of twice-a-day treatment, the severity of wrinkles around the eyes decreased up to 17% after 15 days and 27% following 30 days of treatment.

    Incorporation: Add at the end of the production , at cool down, below 40C.
    Typical Usage Rate: 3 -10%
    Appearance: Water-like liquid, odourless
    Solubility: Water soluble
    Preservative:Phenoxyethanol and Potassium Sorbate
    Long Term Storage: Recommended at 4°C   (39°F)

  • Matrixyl 3000

    Palmitoyl tripeptide-1 (Pal-GHK) &  Palmitoyl Tetrapeptide-3/7 (Pal-GQPR)


    Matrixyl™ 3000 is an anti-aging product from Sederma. Matrikine ™ is the term used for fragmented matrix peptides whom are able to regulate cell activity.

    Matrixyl™ 3000 contains two matrikine peptides, Pal-GHK and Pal-GQPR. Acting as messengers of cutaneous restructuring and repair, these two peptides work synergistically to restore and maintain the skins youthful appearance. As messenger molecules, matrikines™ are capable of regulating cell activities. They interact with specific receptors to activate certain genes involved in the process of extracellular matrix renewal and cell proliferation. With age these mechanisms become progressively weaker. Matrixyl™ 3000 is indicated for anti-aging products and wrinkle treatment products such as gels, serums, lotions and creams.

    Caution: Do not apply this product directly onto your skin.  Add at the end of the emulsion production, at cooling stage, below 40 °C.



    Palmitoyl Tetrapeptide-7 is a synthetic peptide comprised of four amino acids that is used in beauty products and cosmetics to suppress the production of excess interleukins, the chemical messengers which trigger the body’s acute inflammatory response. This can lead to glycation damage, or the process by which glucose links with proteins and causes them to bind together, stiffening tissues. This negatively affects the skin's support system, comprised of collagen, elastin and other proteins, and leads to wrinkles, sagging, and uneven skin tone. this has multiple efficacy on anti aging, promoting anti-wrinkle effect


    Safety Measures/Side Effects:

    There are very few independent studies available on Palmitoyl Tetrapeptide-7. Under its previous name, Palmitoyl Tetrapeptide-3, the EWG found it to be 100% safe for use in cosmetics and beauty products.


    Appearance            Opalescent gel soluble in water
    Odour                     Characteristic
    pH                           4.0-6.0
    Water content        20-30%
    Pal-GHK                 Not less than 0.01%
    Pal-GQPR              Not less than 0.005%

    Aerobic plate          Max 100 cfu/g
    Yeast &  moulds     Max 100 cfu/g
    Escherichia coli       Negative
    Salmonella             Negative

    Long Term Storage: Keep Refrigerated at  4 °C


    INCI: Glycerin and Water and Butylene Glycol and Carbomer and Polysorbate 20 and Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide 7


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